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Zone therapy, also known as reflexology, is a type of alternative medical treatment that uses specialized hand and foot massage as a means of treating mental and physical ailments. Its central foundation rests on the notion that the hands and feet are made up of five major zones on each side of the body that correspond with various health conditions. By massaging a particular zone, a therapist believes he or she can treat the corresponding condition.

The first major zone in zone therapy is referred to as the center zone. This zone is simply the big toes and thumbs on both the left and right sides, which are meant to correspond to the body parts and organs that are located in the center of the body, including the brain, heart, intestines, and reproductive organs. A zone therapist will massage the big toes and thumbs as a means of treating any physical or mental conditions affecting these areas.